ARVCF

armadillo repeat gene deleted in velocardiofacial syndrome

Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.

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Antibodies (6)

Type

Primary (6)

Target

ARVCF (6)

Reactivity

Human (6)

Application

IHC (1)

IHC-P (1)

WB (6)

Host

rabbit (5)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (1)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (5)

Clone

5D2 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (3)

Epitope

C-Terminus (4)

aa75-125 (1)

Publications

No (6)

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IHC-plus™ ARVCF Antibody (clone 5D2) LS-B4284

(4.0) Rating

Antibody:

ARVCF Mouse anti-Human Monoclonal (5D2) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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ARVCF Antibody (aa75-125) LS-C289996

Antibody:

ARVCF Rabbit anti-Human Polyclonal (aa75-125) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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ARVCF Antibody (C-Terminus) LS-C345575

Antibody:

ARVCF Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ARVCF Antibody (C-Terminus, HRP) LS-C467265

Antibody:

ARVCF Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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ARVCF Antibody (C-Terminus, Biotin) LS-C467263

Antibody:

ARVCF Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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ARVCF Antibody (C-Terminus, FITC) LS-C467264

Antibody:

ARVCF Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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