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ART1 /CD296

ADP-ribosyltransferase 1

ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2.

Gene Name: ADP-ribosyltransferase 1
Synonyms: ART1, ADP-ribosyltransferase 2, ART2, ARTC1, CD296, CD296 antigen, ADP-ribosyltransferase 1, Mono(ADP-ribosyl)transferase 1, RT6
Target Sequences: NM_004314 NP_004305.2 P52961

Publications (1)

1
Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity. Julia Hesse, Mona K Rosse, Bodo Steckel, Bernhard Blank-Landeshammer, Svenja Idel, Yvonne Reinders, Albert Sickmann, Norbert Sträter, Jürgen Schrader. Purinergic signalling. 2022 March;18:115-121. [Full Text Article] [PubMed:34961895] [PMC:PMC8850506]

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ART1 /CD296 ELISA Kit
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).