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ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2.
Gene Name: | ADP-ribosyltransferase 1 |
Synonyms: | ART1, ADP-ribosyltransferase 2, ART2, ARTC1, CD296, CD296 antigen, ADP-ribosyltransferase 1, Mono(ADP-ribosyl)transferase 1, RT6 |
Target Sequences: | NM_004314 NP_004305.2 P52961 |
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