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ARSA / Arylsulfatase A
arylsulfatase A
ARSA / Arylsulfatase A hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
| Gene Name: | arylsulfatase A |
| Synonyms: | ARSA, Arylsulfatase A, Cerebroside-sulfatase, MLD, ASA |
| Target Sequences: | NM_000487 NP_000478.3 P15289 |
Publications (3)
1
Acute kidney injury induced by protein-overload nephropathy down-regulates gene expression of hepatic cerebroside sulfotransferase in mice, resulting in reduction of liver and serum sulfatides. Zhang X, Nakajima T, Kamijo Y, Li G, Hu R, Kannagi R, Kyogashima M, Aoyama T, Hara A. Biochemical and biophysical research communications. 2009 390:1382-8.
[PubMed:19895791]
2
Hepatic Cerebroside Sulfotransferase Is Induced by PPAR Activation in Mice. Kimura T, Nakajima T, Kamijo Y, Tanaka N, Wang L, Hara A, Sugiyama E, Tanaka E, Gonzalez FJ, Aoyama T. PPAR research. 2012 2012:174932. (WB; Mouse)
[PubMed:22645601]
[PMC:PMC3356938]
3
Single Systemic Administration of a Gene Therapy Leading to Disease Treatment in Metachromatic Leukodystrophy Arsa Knock-Out Mice. Thia St Martin, Tania A Seabrook, Katherine Gall, Jenn Newman, Nancy Avila, April Hayes, Monicah Kivaa, Jason Lotterhand, Michael Mercaldi, Kruti Patel, Israel J Rivas, Stephen Woodcock, Teresa L Wright, Albert B Seymour, Omar L Francone, Jacinthe Gingras. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023 May;43:3567-3581. [Full Text Article]
[PubMed:36977578]
[PMC:PMC10184740]
Related Antibodies: LS-C688795.
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Products
ELISA Kits
(13)
Type
Custom
(2)
Sandwich
(10)
Sandwich CLIA
(1)
Target
ARSA / Arylsulfatase A
(13)
Reactivity
Human
(7)
Mouse
(1)
Chicken
(1)
Monkey
(1)
Porcine
(1)
Rabbit
(1)
Format
12 x 8-Well Microstrips
(1)
96-Well Microplate
(2)
96-Well Strip Plate
(9)
Publications
No
(13)
Sample Type
Cell Culture Supernatants
(2)
Cell Lysates
(2)
Citrate Plasma
(1)
EDTA Plasma
(1)
Heparin Plasma
(1)
Plasma
(4)
Serum
(5)
Tissue Homogenates
(4)
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich
Human
312 - 20000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$901
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Microplate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$792
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