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ARRB2 / Beta Arrestin 2
arrestin, beta 2
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | arrestin, beta 2 |
| Synonyms: | ARRB2, Arrestin 3, Arrestin beta-2, ARB2, ARR2, BARR2, Arrestin, beta 2, Beta-arrestin-2 |
| Target Sequences: | NM_004313 NP_004304.1 P32121 |
Publications (4)
1
Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys. Zakrzewicz A, Krasteva G, Wilhelm J, Dietrich H, Wilker S, Padberg W, Wygrecka M, Grau V. Immunobiology. 2011 216:854-61.
[PubMed:21193245]
Related Antibodies: LS-C54486.
2
Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of ß-arrestin2. Deborah J Luessen, Haiguo Sun, Molly M McGinnis, Michael Hagstrom, Glen Marrs, Brian A McCool, Rong Chen. The Journal of biological chemistry. 2019 September;294:14068-14080. [Full Text Article]
[PubMed:31366729]
[PMC:PMC6755807]
Related Antibodies: LS-B6008.
3
Pioglitazone Enhances ß-Arrestin2 Signaling and Ameliorates Insulin Resistance in Classical Insulin Target Tissues. Shaimaa El-Fayoumi, Rehab Mansour, Amr Mahmoud, Ahmed Fahmy, Islam Ibrahim. Pharmacology. 2021 June;106:409-417. [Full Text Article]
[PubMed:34082428]
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ARRB2 / Beta Arrestin 2
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Yes
(2)
ARRB2 / Beta Arrestin 2 Mouse anti-Human Monoclonal (3G1) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa23-40) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
ARRB2 / Beta Arrestin 2 Goat anti-Human Polyclonal (aa351-361) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa355-405) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa395-409) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa264-298) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$393
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
20 µl/$275; 100 µl/$389
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ARRB2 / Beta Arrestin 2 Goat anti-Human Polyclonal (Internal Region) (Biotin) Antibody
Mouse, Rat, Human
IHC, IP, Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa151-200) (HRP) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa151-200) (Biotin) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa151-200) (FITC) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ARRB2 / Beta Arrestin 2 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Pig, Human
IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa310-360) Antibody
Human
IHC, IHC-P, IP
Unconjugated
10 µg/$295; 100 µl/$514
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$407
ARRB2 / Beta Arrestin 2 Goat anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µg/$896
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ARRB2 / Beta Arrestin 2 Rabbit anti-Human Polyclonal (aa262-430) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
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