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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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ARPP19
cAMP-regulated phosphoprotein, 19kDa
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
| Gene Name: | cAMP-regulated phosphoprotein, 19kDa |
| Synonyms: | ARPP19, ARPP-16, ARPP16, ENSAL, ARPP-19 |
| Target Sequences: | NM_006628 NP_006619.1 P56211 |
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