Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data.
Gene Name: | ADP-ribosylation factor-like 13B |
Synonyms: | ARL13B, ARL2-like protein 1, ARL2L1, JBTS8 |
Target Sequences: | NM_182896 Q8TCL5 Q3SXY8 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.