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ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 7
Synonyms: ARHGEF7, COOL1, COOL-1, Hypothetical protein kiaa0142, Nbla10314, p85, p85COOL1, p85SPR, PIXB, KIAA0142, p50, PAK3BP, BETA-PIX, p50BP
Target Sequences: NM_003899 NP_003890.1 Q14155

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Products
Antibodies (31)
Primary (31)
ARHGEF7 (31)
Human (31)
Mouse (11)
Rat (18)
IHC (10)
IHC-P (5)
WB (31)
ELISA (11)
ICC (1)
IP (1)
Peptide-ELISA (2)
rabbit (31)
Product Group
IHCPlus (1)
Ig (1)
IgG (17)
polyclonal pc (31)
APC (1)
APC Conjugated (2)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (16)
aa1-188 (8)
280-360 aa, Internal (1)
C-Terminus (1)
Gln344 (1)
Internal (1)
aa246-450 (1)
aa311-360 (1)
No (31)
ARHGEF7 Antibody - Western blot analysis of lysates from rat muscle and rat heart cells, using ARHGEF7 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
ARHGEF7 Rabbit anti-Human Polyclonal (aa311-360) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGEF7 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ARHGEF7 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ARHGEF7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
ARHGEF7 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ARHGEF7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
ARHGEF7 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ARHGEF7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
ARHGEF7 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using ARHGEF7 Polyclonal Antibody at dilution of 1:40.
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ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ARHGEF7 Antibody - Western blot analysis using anti-beta-Pix (mouse), pAb . 1: Mouse brain lysates (30 ug). 2: NIH3T3 whole cell lysates (30 ug). . * beta-Pix is a major isoform in NIH3T3 lysates, while other beta-Pix isoforms are also detected in mouse brain lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF7 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, WB
Unconjugated
100 µg/$323
Select
ARHGEF7 Rabbit anti-Human Polyclonal (280-360 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ARHGEF7 Antibody - Immunohistochemical analysis of ARHGEF7 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ARHGEF7 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Select
ARHGEF7 Rabbit anti-Human Polyclonal (Gln344) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
ARHGEF7 Antibody - Western blot of ARHGEF7 pAb in extracts from Jurkat, COS1, COS7, MCF7, K562 cells and mouse lung, heart tissues.
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ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
ARHGEF7 Antibody - Western blot analysis of extracts of various cell lines, using ARHGEF7 antibody at 1:500 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ARHGEF7 Antibody - Western blot of ARHGEF7 antibody
Select
ARHGEF7 Rabbit anti-Human Polyclonal (aa246-450) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
ARHGEF7 Antibody - All lanes: Anti-ARHGEF7 Antibody (C-Term) at 1:2000 dilution Lane 1: Jurkat whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: NIH/3T3 whole cell lysate Lane 4: ZR-75-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 90 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
ARHGEF7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
ARHGEF7 Antibody - Western blot analysis of extracts from rat muscle cells and rat heart cells, using ARHGEF7 antibody.
Select
ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ARHGEF7 Antibody - Western blot analysis of extracts of rat muscle cells using ARHGEF7 antibody. The lane on the left is treated with the antigen-specific peptide.
Select
ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ARHGEF7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
ARHGEF7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
ARHGEF7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
ARHGEF7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
ARHGEF7 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
ARHGEF7 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
ARHGEF7 Antibody - Western blot of ARHGEF7 antibody.
Select
ARHGEF7 Rabbit anti-Rat Polyclonal (aa1-188) Antibody
Rat, Human
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
ARHGEF7 Antibody - Western blot of ARHGEF7 antibody.
Select
ARHGEF7 Rabbit anti-Rat Polyclonal (aa1-188) (FITC) Antibody
Rat, Human
WB
FITC Conjugated
100 µl/$359; 200 µl/$423; 500 µl/$655; 1 ml/$816; 2 ml/$1,055; 5 ml/$1,863
Viewing 1-25 of 31 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).