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ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.
| Gene Name: | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| Synonyms: | ARHGEF18, p114-RhoGEF, KIAA0521, SA-RhoGEF, Septin-associated RhoGEF, p114RhoGEF, p114-RHO-GEF |
| Target Sequences: | NM_015318 NP_056133.2 Q6ZSZ5 |
☰ Filters
Products
Antibodies
(22)
Type
Primary
(22)
Target
ARHGEF18
(22)
Reactivity
Human
(22)
Dog
(4)
Application
IHC
(7)
IHC-P
(4)
WB
(18)
ELISA
(15)
ICC
(1)
Peptide-ELISA
(1)
Host
rabbit
(17)
mouse
(4)
goat
(1)
Product Group
IHCPlus
(1)
Isotype
IgG
(16)
IgG1
(4)
Clonality
monoclonal mc
(4)
polyclonal pc
(18)
Clone
OTI4B5
(1)
OTI6D10
(2)
OTI6G8
(1)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(3)
Carrier-free
(1)
FITC Conjugated
(3)
HRP Conjugated
(3)
PE Conjugated
(1)
Unconjugated
(11)
Epitope
aa91-119
(7)
aa118-215
(4)
aa1160-1173
(1)
aa770-990
(1)
Publications
No
(22)
ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ARHGEF18 Rabbit anti-Human Polyclonal (HRP) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Rabbit anti-Human Polyclonal (Biotin) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Rabbit anti-Human Polyclonal (FITC) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI6D10) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (Carrier-free) (OTI6D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
ARHGEF18 Rabbit anti-Human Polyclonal (aa770-990) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ARHGEF18 Goat anti-Human Polyclonal (aa1160-1173) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI4B5) Antibody
Human
WB
Unconjugated
100 µl/$434
ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI6G8) Antibody
Human
WB
Unconjugated
100 µl/$434
ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) Antibody
Human
WB
Unconjugated
400 µl/$393
ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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