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May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Gene Name: | Rho guanine nucleotide exchange factor (GEF) 12 |
Synonyms: | ARHGEF12, KIAA0382, LARG, PRO2792, Leukemia-associated RhoGEF |
Target Sequences: | NM_015313 NP_056128.1 Q9NZN5 |
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