ARHGAP35 / GRLF1

Rho GTPase activating protein 35

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

ARHGAP35 / GRLF1 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ARHGAP35 / GRLF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76146

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

172.18 kDa

Price:

20 µg/$215

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ARHGAP35 / GRLF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116611

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

172.18 kDa

Price:

100 µg/$710

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Human ARHGAP35 / GRLF1 Protein (Recombinant GST) (Full Length) - LS-G28721

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

29.7 kDa

Price:

10 µg/$479; 25 µg/$670

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