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ARHGAP32 / RICS / p250GAP
Rho GTPase activating protein 32
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity.
| Gene Name: | Rho GTPase activating protein 32 |
| Synonyms: | ARHGAP32, GC-GAP, GAB-associated CDC42, GRIT, p200RhoGAP, Rac GTPase activating protein, RICS, PX-RICS, KIAA0712, p250GAP |
| Target Sequences: | NM_014715 NP_055530.2 A7KAX9 |
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