ARHGAP17 / NADRIN

Rho GTPase activating protein 17

Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ARHGAP17 / NADRIN (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ARHGAP17 / NADRIN Protein (Recombinant GST) (Full Length) - LS-G34184

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

121.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARHGAP17 / NADRIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86001

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.3 kDa

Price:

20 µg/$150

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Human ARHGAP17 / NADRIN Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69986

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.3 kDa

Price:

20 µg/$1,107

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ARHGAP17 / NADRIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122031

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.3 kDa

Price:

100 µg/$494

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