ARH / LDLRAP1

low density lipoprotein receptor adaptor protein 1

Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

ARH / LDLRAP1 (6)

Publications

No (6)

Tag

GST (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human ARH / LDLRAP1 Protein (Recombinant His) - LS-G1617

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human ARH / LDLRAP1 Protein (Recombinant GST) (Full Length) - LS-G33095

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.67 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARH / LDLRAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92883

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.7 kDa

Price:

20 µg/$150

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Human ARH / LDLRAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72561

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.7 kDa

Price:

20 µg/$1,107

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ARH / LDLRAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113132

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.7 kDa

Price:

100 µg/$494

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Mouse ARH / LDLRAP1 Protein (Recombinant His) (aa1-308) - LS-G25217

Source:

E. coli

Tag:

His

Molecular Weight:

37.7 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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