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ARFGAP1

ADP-ribosylation factor GTPase activating protein 1

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Gene Name: ADP-ribosylation factor GTPase activating protein 1
Synonyms: ARFGAP1, ARF GAP 1, ARF1GAP, ARF1 GAP, BA261N11.3, GAP protein, HRIHFB2281
Target Sequences: NM_018209 NP_060679.1 Q8N6T3

Publications (1)

1
Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:7444-8. [PubMed:17460038] [PMC:PMC1863490]

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Antibodies (52)
Primary (52)
ARFGAP1 (52)
Human (52)
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rabbit (29)
mouse (17)
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aa377-406 (7)
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aa11-204 (1)
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ARFGAP1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-ARFGAP1 mouse monoclonal antibody.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI1H4) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-ARFGAP1 mouse monoclonal antibody.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ARFGAP1 mouse monoclonal antibody.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI1F6) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ARFGAP1 mouse monoclonal antibody.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F6) Antibody
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI1H6) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H6) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI2C6) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C6) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI2C5) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C5) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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ARFGAP1 Rabbit anti-Human Polyclonal (140-220 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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ARFGAP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (OTI 2C10) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
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ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI 2C10) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Western blot analysis using ARFGAP1 mouse mAb against MOLT4 (1), C2C12 (2), HepG2 (3), MCF-7 (4), and Lncap (5) cell lysate.
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ARFGAP1 Mouse anti-Human Monoclonal (1C4E2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
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ARFGAP1 Rabbit anti-Human Polyclonal (aa1-220) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded rat brain using ARFGAP1 antibody at dilution of 1:100 (40x lens).
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ARFGAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
ARFGAP1 Mouse anti-Human Monoclonal (OTI1F9) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F9) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
ARFGAP1 Mouse anti-Human Monoclonal (OTI2D5) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
ARFGAP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2D5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
Select
ARFGAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
ARFGAP1 Rabbit anti-Human Polyclonal (aa377-406) Antibody
Rabbit, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ARFGAP1 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using ARFGAP1 antibody.
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ARFGAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ARFGAP1 Antibody
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ARFGAP1 Rabbit anti-Human Polyclonal (aa11-204) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
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