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ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
Gene Name: | ADP-ribosylation factor 3 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | ARF3, ADP-ribosylation factor 3, Small GTP binding protein |
Target Sequences: | NM_001659 NP_001650.1 P61204 |
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