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ARA55 / HIC-5

transforming growth factor beta 1 induced transcript 1

Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.

Gene Name: transforming growth factor beta 1 induced transcript 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB1I1, ARA55, HIC5, HIC-5, TSC-5
Target Sequences: NM_015927 NP_057011.2 O43294

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Products
Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
ARA55 / HIC-5 (9)
No (9)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (6)
Human (6)
Rat (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (1)
ARA55 / HIC-5 Protein - Recombinant Transforming Growth Factor Beta 1 Induced Transcript 1 By SDS-PAGE
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E. coli
His-T7
27.0 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
ARA55 / HIC-5 Protein
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E. coli
None
27.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ARA55 / HIC-5 Protein - 12.5% SDS-PAGE of human TGFB1I1 stained with Coomassie Blue
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Wheat Germ Extract
GST
74.58 kDa
2 µg/$439
ARA55 / HIC-5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.8 kDa
100 µg/$494
ARA55 / HIC-5 Protein - Purified recombinant protein TGFB1I1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$1,107
ARA55 / HIC-5 Protein - Purified recombinant protein TGFB1I1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$1,107
ARA55 / HIC-5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
47.8 kDa
100 µg/$494
Select
293T Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$150
ARA55 / HIC-5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
47.8 kDa
20 µg/$150
Viewing 1-9 of 9 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).