AR / Androgen Receptor

androgen receptor

The androgen receptor (AR) is a NR3 Steroid Receptor located on the X chromosome. AR is a phosphoprotein and acts as a steroid hormone-activated transcription factor for androgen-responsive genes. Mutations in the AR gene are associated with androgen insensitivity syndrome (CAIS) or testicular feminization syndrome, Reifenstein syndrome, and Kennedy spinal and bulbar muscular atrophy. They lead to symptoms such as low virilization, reduced sperm production, testicular atrophy, and infertility. Androgen signaling through the androgen receptor (AR) appears to be involved in all aspects of prostate cancer, from initiation to development of treatment resistance. Gain-of-function AR gene mutations and/or altered signaling through AR have been suggested to contribute to disease progression. A recent study showed decreased expression of AR in response to incubation of LNCaP prostate carcinoma cells with PC-SPES, a mixture of eight herbs (Bonham et al. 2002). Two forms of AR that differ in their N termini have been isolated: AR A (87 kD), which is derived from translation of an internal methionine codon (met188), and AR B (110 kD). The two isoforms are expressed in similar tissues; however, AR B generally is the more abundant form.

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Products

ELISA Kits (24)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Competitive EIA (1)

Custom (2)

Development Kit (1)

DNA Binding Phosphorylation (2)

Sandwich (13)

Sandwich CLIA (2)

Target

AR / Androgen Receptor (24)

Reactivity

Human (11)

Mouse (7)

Rat (7)

Chicken (1)

Dog (1)

Monkey (1)

Pig (1)

Rabbit (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (4)

96-Well Strip Plate (15)

Antibody Pair and Standard (1)

Publications

No (23)

Yes (1)

Sample Type

Adherent Cell Cultures (3)

Cell Culture Supernatants (2)

Cell Lysates (6)

Nuclear Lysates (2)

Plasma (11)

Serum (11)

Tissue Homogenates (5)

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Rat AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F6438

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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Mouse AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F16608

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human AR / Androgen Receptor (CLIA) ELISA Kit - LS-F29439

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F4505

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Ser650) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F855

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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Human AR / Androgen Receptor (Cell-Based ELISA) ELISA Kit - LS-F1796

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F21949

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Dog AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F16604

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F34435

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

Select

Monkey AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F41052

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F13061

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Tyr363) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1704

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat Phospho-AR / Androgen Receptor (Tyr363) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F856

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

Select

Human Phospho-AR / Androgen Receptor (Ser650) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1762

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$641

Select

Mouse AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F6268

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$715

Select

Pig AR / Androgen Receptor (Custom ELISA) ELISA Kit - LS-F16605

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat AR / Androgen Receptor (Custom ELISA) ELISA Kit - LS-F16606

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Chicken AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F41051

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F41054

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Mouse AR / Androgen Receptor (CLIA) ELISA Kit - LS-F30838

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

DevKit DuoPlus Rat AR / Androgen Receptor ELISA Development Kit - LS-F72125

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,305; 1000 Wells/$1,952

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Rat AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F27351

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Mouse AR / Androgen Receptor (Competitive EIA) ELISA Kit - LS-F28189

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human AR / Androgen Receptor (Sandwich ELISA) ELISA Kit - LS-F26680

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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