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AQP1 / Aquaporin 1

aquaporin 1 (Colton blood group)

Aquaporin-1 (AQP1), also known as Channel-forming integral membrane protein (CHIP), is the first member of the aquaporin water channel family. It plays a role in the transmembrane water transport, especially in kidneys, red blood cells, central nervous system and some epithelial surfaces. Its activity can be blocked by mercurial compounds. AQP1 is associated with so-called Colton blood group antigens. Rare individuals, who do not express these antigens and whose red cells exhibit low osmotic water permeabilities, contain deleterious homozygous germ-line mutations in the AQP1 gene; however, this condition is not accompanied by visible clinical consequence.

Gene Name: aquaporin 1 (Colton blood group)
Family/Subfamily: Transporter , Aquaporin
Synonyms: AQP1, Aquaporin-1, AQP-1, AQP-CHIP, Aquaporin 1, Aquaporin-CHIP, CHIP28, Colton blood group, Urine water channel, CO
Target Sequences: NM_198098 NP_932766.1 P29972

Publications (1)

1
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis. Ejaife O Agbani , Christopher M Williams, Yong Li, Marion Tj van den Bosch, Samantha F Moore, Adele Mauroux, Lorna Hodgson, Alan S Verkman, Ingeborg Hers, Alastair W Poole. JCI insight. 2018 May;3:e99062. [Full Text Article] [PubMed:29769447] [PMC:PMC6012506]

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Products
Antibodies (60)
Primary (60)
AQP1 / Aquaporin 1 (60)
Human (51)
Mouse (26)
Rat (27)
Bovine (3)
Monkey (1)
Sheep (3)
IHC (28)
IHC-Fr (3)
IHC-P (21)
WB (52)
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ELISA (27)
ICC (2)
IF (6)
IP (4)
Peptide-ELISA (2)
rabbit (50)
mouse (10)
Product Group
IHCPlus (9)
IgG (34)
IgG1 (10)
monoclonal mc (10)
polyclonal pc (50)
1/A5F6 (2)
10C11 (2)
1F3 (2)
7D11 (1)
OTI2D10 (2)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
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Unconjugated (34)
aa201-269 (8)
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70-150 aa, Internal (1)
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No (60)
AQP1 / Aquaporin 1 Antibody - Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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AQP1 / Aquaporin 1 Mouse anti-Rat Monoclonal (aa249-269) (Concentrated) (1/A5F6) Antibody
Rat
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
0.05 mg/$485
AQP1 / Aquaporin 1 Antibody - Anti-AQP1 / Aquaporin 1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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AQP1 / Aquaporin 1 Rabbit Polyclonal (aa1-10) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa243-261) (Biotin) Antibody
Mouse, Sheep, Bovine, Rat, Human
IHC, WB
Biotin Conjugated
50 µl/$1,054
AQP1 / Aquaporin 1 Antibody - Anti-AQP1 / Aquaporin 1 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (1F3) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Antibody - Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa241-269) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (OTI2D10) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-AQP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2D10) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (10C11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Antibody - Anti-AQP1 / Aquaporin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Antibody - 1:100 staining human kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AQP1 / Aquaporin 1 Antibody - IHC-P: AQP1 antibody testing of human kidney cancer tissue
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa251-269) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
AQP1 / Aquaporin 1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
AQP1 / Aquaporin 1 Antibody - Western blot of recombinant AQP1 / Aquaporin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa201-269) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
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AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (aa249-269) (1/A5F6) Antibody
Human
ELISA, IF, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$565
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$564
AQP1 / Aquaporin 1 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using AQP1 Antibody at dilution of 1:100
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
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AQP1 / Aquaporin 1 Mouse anti-Rat Monoclonal (aa249-269) Antibody
Mouse, Rat
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$884
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AQP1 / Aquaporin 1 Mouse anti-Rat Monoclonal (aa198-208) (7D11) Antibody
Rat
ELISA, Flo, IHC-P, WB
Unconjugated
0.1 mg/$565
AQP1 / Aquaporin 1 Antibody - Aquaporin 1 antibody IHC-paraffin. IHC(P): Mouse Kidney Tissue.
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa240-269) Antibody
Mouse, Sheep, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
AQP1 / Aquaporin 1 Antibody
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AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).