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AQP1 / Aquaporin 1
aquaporin 1 (Colton blood group)
Aquaporin-1 (AQP1), also known as Channel-forming integral membrane protein (CHIP), is the first member of the aquaporin water channel family. It plays a role in the transmembrane water transport, especially in kidneys, red blood cells, central nervous system and some epithelial surfaces. Its activity can be blocked by mercurial compounds. AQP1 is associated with so-called Colton blood group antigens. Rare individuals, who do not express these antigens and whose red cells exhibit low osmotic water permeabilities, contain deleterious homozygous germ-line mutations in the AQP1 gene; however, this condition is not accompanied by visible clinical consequence.
| Gene Name: | aquaporin 1 (Colton blood group) |
| Family/Subfamily: | Transporter , Aquaporin |
| Synonyms: | AQP1, Aquaporin-1, AQP-1, AQP-CHIP, Aquaporin 1, Aquaporin-CHIP, CHIP28, Colton blood group, Urine water channel, CO |
| Target Sequences: | NM_198098 NP_932766.1 P29972 |
Publications (1)
1
Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis. Ejaife O Agbani , Christopher M Williams, Yong Li, Marion Tj van den Bosch, Samantha F Moore, Adele Mauroux, Lorna Hodgson, Alan S Verkman, Ingeborg Hers, Alastair W Poole. JCI insight. 2018 May;3:e99062. [Full Text Article]
[PubMed:29769447]
[PMC:PMC6012506]
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AQP1 / Aquaporin 1 Mouse anti-Rat Monoclonal (aa249-269) (Concentrated) (1/A5F6) Antibody
Rat
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
0.05 mg/$485
AQP1 / Aquaporin 1 Rabbit Polyclonal (aa1-10) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa243-261) (Biotin) Antibody
Mouse, Sheep, Bovine, Rat, Human
IHC, WB
Biotin Conjugated
50 µl/$1,054
AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (1F3) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa241-269) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (OTI2D10) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2D10) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Development Kit
Antibody Pair and Standard
Human
0.5 - 32 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,041; 1000 Wells/$1,512
Sandwich
96-Well Microplate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (10C11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Sandwich
96-Well Strip Plate
Human
0.25 - 16 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
HEK 293 Cells
Myc-DDK (Flag)
28.3 kDa
20 µg/$1,107
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa251-269) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (aa201-269) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
AQP1 / Aquaporin 1 Mouse anti-Human Monoclonal (aa249-269) (1/A5F6) Antibody
Human
ELISA, IF, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$565
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$564
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
AQP1 / Aquaporin 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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