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APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants.
Gene Name: | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
Synonyms: | APPBP2, APP-BP2, KIAA0228, HS.84084, PAT1 |
Target Sequences: | NM_006380 NP_006371.2 Q92624 |
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