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APOE / Apolipoprotein E

apolipoprotein E

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Gene Name: apolipoprotein E
Synonyms: APOE, AD2, Apo-E, Apolipoprotein E3, Apolipoprotein E, LDLCQ5, LPG
Target Sequences: NM_000041 NP_000032.1 P02649

Publications (2)

1
A proteomic approach for the diagnosis of bacterial meningitis. Jesse S, Steinacker P, Lehnert S, Sdzuj M, Cepek L, Tumani H, Jahn O, Schmidt H, Otto M. PloS one. 2010 5:e10079. (WB) [PubMed:20386697] [PMC:PMC2851643]
2
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model. Leticia Rodrigues, Krista Minéia Wartchow, Michael Buchfelder, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Andrea Kleindienst. International journal of molecular sciences. 2022 August;23: [Full Text Article] [PubMed:36076994] [PMC:PMC9455494]

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APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Microplate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$675
APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Microplate
Rat
15.6 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$734
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
APOE / Apolipoprotein E ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
0.82 - 600 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$851
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Competitive EIA
96-Well Microplate
Human
15.62 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$675
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Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Milk, Plasma, Saliva, Serum, Urine
1 Plate/$699
APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
5 - 100 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$748
APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Microplate
Pig
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$675
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Human
1.638 - 160 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Human
61.44 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$604
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Human
0.41 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$733
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Human
0.41 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$760
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
4.69 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$598
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
APOE / Apolipoprotein E ELISA Kit
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Development Kit
Antibody Pair and Standard
Rat
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
APOE / Apolipoprotein E ELISA Kit
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Development Kit
Antibody Pair and Standard
Human
9.4 - 600 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$992; 1000 Wells/$1,430
APOE / Apolipoprotein E ELISA Kit
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Development Kit
Antibody Pair and Standard
Mouse
31.2 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,207; 1000 Wells/$1,787
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).