Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

APOA1 / Apolipoprotein A 1

apolipoprotein A-I

APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18-amino acid signal peptide is removed co-translationally and a 6-amino acid propeptide is cleaved post-translationally. Variation in the latter step, in addition to modifications leading to so-called isoforms, is responsible for some of the polymorphism observed. APOA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the C-III gene is transcribed convergently in relation to A-I. Defects in the apolipoprotein A-1 gene are associated with HDL deficiency and Tangier disease.

Gene Name: apolipoprotein A-I
Synonyms: APOA1, ApoA-I, APOAI, Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Target Sequences: NM_000039 NP_000030.1 P02647

Publications (6)

1
Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I. Duong PT, Collins HL, Nickel M, Lund-Katz S, Rothblat GH, Phillips MC. Journal of lipid research. 2006 47:832-43. [PubMed:16418537]
2
A microbial TLR2 agonist imparts macrophage-activating ability to apolipoprotein A-1. Hasebe A, Pennock ND, Mu HH, Chan FV, Taylor ML, Cole BC. Journal of immunology (Baltimore, Md. : 1950). 2006 177:4826-32. [PubMed:16982924]
3
Tmprss3 loss of function impairs cochlear inner hair cell Kcnma1 channel membrane expression. Molina L, Fasquelle L, Nouvian R, Salvetat N, Scott HS, Guipponi M, Molina F, Puel JL, Delprat B. Human molecular genetics. 2013 22:1289-99. (ICC, IHC; Mouse) [PubMed:23255163]
4
Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial. Graham SM, Chen J, Chung DW, Barker KR, Conroy AL, Hawkes MT, Namasopo S, Kain KC, López JA, Liles WC. Malaria journal. 2016 15:56. (ELISA; Human) [Full Text Article] [PubMed:26830467] [PMC:PMC4736470] Related Antibodies: LS-C11247.
5
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men. Graham SM, Chen J, Le J, Ling M, Chung DW, Liles WC, López JA. International journal of medical sciences. 2019 January;16:276-284. [Full Text Article] [PubMed:30745808] [PMC:PMC6367531] Related Antibodies: LS-C11247.
6
Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits. Haizhao Yan , Manabu Niimi , Fumikazu Matsuhisa , Huanjin Zhou, Shuji Kitajima, Yajie Chen, Chuan Wang, Xiawen Yang, Jian Yao, Dongshan Yang, Jifeng Zhang, Masami Murakami, Katsuyuki Nakajima, Yao Wang, Enqi Liu, Jingyan Liang, Y Eugene Chen, Jianglin Fan. Arteriosclerosis, thrombosis, and vascular biology. 2020 September;40:2095-2107. [Full Text Article] [PubMed:32757647] Related Antibodies: LS-C314186.
more

☰ Filters
Products
ELISA Kits (46)
Competitive EIA (5)
Custom (5)
Development Kit (4)
Sandwich (27)
Sandwich CLIA (5)
APOA1 / Apolipoprotein A 1 (46)
Human (12)
Mouse (7)
Rat (6)
Bovine (1)
Chicken (1)
Dog (3)
Guinea pig (1)
Monkey (3)
Pig (4)
Rabbit (5)
Rhesus monkey (1)
Sheep (1)
Product Group
DevKit DuoPlus (4)
12 x 8-Well Microstrips (3)
96-Well Microplate (3)
96-Well Strip Plate (36)
Antibody Pair and Standard (4)
No (46)
Cell Culture Supernatants (13)
Cell Lysates (9)
Cell Supernatant (1)
Plasma (40)
Saliva (1)
Serum (40)
Tissue Homogenates (18)
Urine (3)
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.4 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Saliva, Serum, Urine
1 Plate/$788
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$705
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
1.563 - 90 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.21 - 150 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$741
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rhesus monkey
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$826
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
0.14 - 100 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$871
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$748
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Dog
28.12 - 1800 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Bovine
78 - 5000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rabbit
24.69 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$741
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.082 - 8 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
28.13 - 1800 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.781 - 50 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3120 - 200000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$582
APOA1 / Apolipoprotein A 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-25 of 46 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).