APITD1

apoptosis-inducing, TAF9-like domain 1

DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Required for optimal chromatin association of the FA core complex. Required for efficient damage-induced monoubiquitination and focus formation of FANCD2. Stabilizes FAAD24, FANCM and STRA13/CENPX in the FA core complex. Plays a role in DNA interstrand cross-linking (ICL) repair and in recovery of replication forks stalled by topoisomerase I-DNA cleavage intermediates induced by camptothecin. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation. Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

APITD1 (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human APITD1 Protein (Recombinant GST) (Full Length) - LS-G37395

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human APITD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94807

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.9 kDa

Price:

20 µg/$150

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Human APITD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94809

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.5 kDa

Price:

20 µg/$150

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Human APITD1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G73271

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.1 kDa

Price:

20 µg/$1,107

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APITD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130650

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.5 kDa

Price:

100 µg/$494

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APITD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103614

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.9 kDa

Price:

100 µg/$494

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