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APCS / Serum Amyloid P / SAP

amyloid P component, serum

APCS / Serum Amyloid P / SAP is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Gene Name: amyloid P component, serum
Synonyms: APCS, 9.5S alpha-1-glycoprotein, Amyloid P component, serum, Pentaxin-related, PTX2, Serum Amyloid P, Serum amyloid P-component, SAP
Target Sequences: NM_001639 NP_001630.1 P02743

Publications (1)

1
The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Martin R Späth, Malte P Bartram, Nicolàs Palacio-Escat, K Johanna R Hoyer, Cedric Debes, Fatih Demir, Christina B Schroeter, Amrei M Mandel, Franziska Grundmann, Giuliano Ciarimboli, Andreas Beyer, Jayachandran N Kizhakkedathu, Susanne Brodesser, Heike Göbel, Jan U Becker, Thomas Benzing, Bernhard Schermer, Martin Höhne, Volker Burst, Julio Saez-Rodriguez, Pitter F Huesgen, Roman-Ulrich Müller, Markus M Rinschen. Kidney international. 2019 February;95:333-349. [Full Text Article] [PubMed:30522767] Related Antibodies: LS-B11917.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (2)
Recombinant (16)
APCS / Serum Amyloid P / SAP (18)
No (18)
6His, C-terminus (4)
6His, N-terminus (1)
GST (1)
GST, N-terminus (3)
His (4)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (11)
Mouse (4)
Rat (2)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Human Cells (4)
Mammalian Cells (2)
Wheat Germ Extract (3)
Purified (3)
Low endotoxin level (6)
APCS / Serum Amyloid P / SAP Protein - Recombinant Serum Amyloid P Component By SDS-PAGE
Select
E. coli
His
24.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
APCS / Serum Amyloid P / SAP Protein - Recombinant Serum Amyloid P Component By SDS-PAGE
Select
E. coli
His
24.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
E. coli
His-GST
50.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.9kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.2kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
APCS / Serum Amyloid P / SAP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
APCS / Serum Amyloid P / SAP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
25.3 kDa
100 µg/$721
APCS / Serum Amyloid P / SAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.39 kDa
100 µg/$494
APCS / Serum Amyloid P / SAP Protein - Purified recombinant protein APCS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
23.2 kDa
20 µg/$1,107
APCS / Serum Amyloid P / SAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.39 kDa
20 µg/$150
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.2 kDa
10 µg/$269; 50 µg/$368
APCS / Serum Amyloid P / SAP Protein - Recombinant Serum Amyloid P Component (SAP) by SDS-PAGE
Select
E. coli
His, N-Terminal
25.5kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.9 kDa
10 µg/$317; 50 µg/$524
APCS / Serum Amyloid P / SAP Protein - 12.5% SDS-PAGE of human APCS stained with Coomassie Blue
Select
Wheat Germ Extract
GST
50.27 kDa
10 µg/$479; 25 µg/$670
APCS / Serum Amyloid P / SAP Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
26 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
APCS / Serum Amyloid P / SAP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
25.3 kDa
100 µg/$721
Viewing 1-18 of 18 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).