APC

Adenomatous Polyposis Coli

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

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Products

ELISA Kits (16)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (2)

Sandwich (9)

Sandwich CLIA (3)

Target

APC (16)

Reactivity

Human (7)

Mouse (5)

Rat (2)

Guinea pig (1)

Monkey (2)

Porcine (1)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (2)

96-Well Strip Plate (10)

Publications

No (16)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (2)

Plasma (7)

Serum (7)

Tissue Homogenates (3)

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Porcine APC (Sandwich ELISA) ELISA Kit - LS-F44277

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.63 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Mouse APC (Sandwich ELISA) ELISA Kit - LS-F39613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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Human APC (Sandwich ELISA) ELISA Kit - LS-F10849

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human APC (Sandwich ELISA) ELISA Kit - LS-F6613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse APC (Sandwich ELISA) ELISA Kit - LS-F38491

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human Phospho-APC (Ser2054) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1314

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat APC (Cell-Based ELISA) ELISA Kit - LS-F1801

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Mouse APC (Custom ELISA) ELISA Kit - LS-F15991

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat APC (Custom ELISA) ELISA Kit - LS-F15992

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human APC (CLIA) ELISA Kit - LS-F30099

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse APC (CLIA) ELISA Kit - LS-F30701

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

1.563 - 100 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human APC (Sandwich ELISA) ELISA Kit - LS-F34412

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Monkey APC (Sandwich ELISA) ELISA Kit - LS-F40794

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human APC (CLIA) ELISA Kit - LS-F29400

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Guinea pig APC (Sandwich ELISA) ELISA Kit - LS-F44276

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

31.25 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey APC (Sandwich ELISA) ELISA Kit - LS-F44278

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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