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APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

APBA2 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: amyloid beta (A4) precursor protein-binding, family A, member 2
Synonyms: APBA2, D15S1518E, Adapter protein X11beta, LIN-10, MGC:14091, Mint-2, MINT2, X11-BETA, X11-like, HsT16821, Neuron-specific X11L protein, X11-like protein, X11L
Target Sequences: NM_005503 NP_005494.2 Q99767

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
APBA2 (3)
No (3)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
APBA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
81.1 kDa
20 µg/$215
APBA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
81.1 kDa
100 µg/$710
APBA2 Protein - Recombinant  Amyloid Beta Precursor Protein Binding Protein A2 By SDS-PAGE
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E. coli
His-T7
32.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).