APAF1 / APAF-1

apoptotic peptidase activating factor 1

Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations. Apaf1-deficient embryos display an interesting phenotype in the inner ear and in limb development, which involves different caspase-dependent and -independent pathways. Moreover, APAF1 is mutated in human melanomas, and its depletion contributes to malignant transformation in a mouse model of cancer.

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Products

ELISA Kits (23)

Type

Cell-Based (1)

Custom (3)

Sandwich (14)

Sandwich CLIA (5)

Target

APAF1 / APAF-1 (23)

Reactivity

Human (8)

Mouse (6)

Rat (4)

Chicken (1)

Dog (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (3)

96-Well Strip Plate (18)

Publications

No (22)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (3)

Plasma (9)

Serum (9)

Tissue Homogenates (9)

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Rat APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F8140

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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Human APAF1 / APAF-1 (Cell-Based ELISA) ELISA Kit - LS-F1800

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Rat APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F10848

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F34467

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Chicken APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F41399

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F41400

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F41401

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F41403

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Mouse APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F38980

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$715

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Human APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F35405

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F35404

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human APAF1 / APAF-1 (CLIA) ELISA Kit - LS-F29424

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Mouse APAF1 / APAF-1 (CLIA) ELISA Kit - LS-F30500

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

6.25 - 400 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F20933

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F4412

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

Select

Human APAF1 / APAF-1 (Custom ELISA) ELISA Kit - LS-F15800

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse APAF1 / APAF-1 (Custom ELISA) ELISA Kit - LS-F15801

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Dog APAF1 / APAF-1 (Custom ELISA) ELISA Kit - LS-F15802

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human APAF1 / APAF-1 (CLIA) ELISA Kit - LS-F26101

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

13.72 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Tissue Homogenates

Price:

1 Plate/$851

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Mouse APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F24156

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Mouse APAF1 / APAF-1 (CLIA) ELISA Kit - LS-F26238

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

13.72 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Tissue Homogenates

Price:

1 Plate/$871

Select

Rat APAF1 / APAF-1 (CLIA) ELISA Kit - LS-F26239

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

13.72 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Tissue Homogenates

Price:

1 Plate/$911

Select

Human APAF1 / APAF-1 (Sandwich ELISA) ELISA Kit - LS-F26678

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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