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AP3S2
adaptor-related protein complex 3, sigma 2 subunit
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
| Gene Name: | adaptor-related protein complex 3, sigma 2 subunit |
| Synonyms: | AP3S2, AP-3 complex subunit sigma-3B, AP3S3, AP-3 complex subunit sigma-2, Adaptor complex sigma3B, Sigma-adaptin 3b, Sigma3B-adaptin, Sigma-3B-adaptin, Sigma3b |
| Target Sequences: | NM_005829 NP_005820.1 P59780 |
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