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AP3B1

adaptor-related protein complex 3, beta 1 subunit

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Gene Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: AP3B1, ADTB3A, AP-3 complex beta-3A subunit, Ap-3 complex beta3a subunit, Beta-3A-adaptin, Beta3A-adaptin, ADTB3, HPS2, HPS, PE, AP-3 complex subunit beta-1
Target Sequences: NM_003664 NP_003655.3 O00203

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AP3B1 ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$730
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).