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ANXA8 / Annexin A8

annexin A8

Annexin VIII (ANXA8) belongs to the family of Ca (2+) dependent phospholipid binding proteins (annexins), and has a high 56% identity to annexin V (vascular anticoagulant-alpha). It was initially isolated as 2.2 kb vascular anticoagulant-beta transcript from human placenta, a Ca (2+) dependent phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. However, the fact that annexin VIII is neither an extracellular protein nor associated with the cell surface suggests that it may not play a role in blood coagulation in vivo and its physiological role remains unknown. It is expressed at low levels in human placenta and shows restricted expression in lung endothelia, skin, liver, and kidney. The gene is also found to be selectively overexpressed in acute myelocytic leukemia.

Gene Name: annexin A8
Synonyms: ANXA8, Annexin A8, Annexin-8, ANX8, Vascular anticoagulant-beta, Annexin VIII, VAC-beta
Target Sequences: NM_001040084 NP_001035173.1 P13928

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
ANXA8 / Annexin A8 (9)
No (9)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (3)
Human (8)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
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E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
36.9kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
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Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
ANXA8 / Annexin A8 Protein - Purified recombinant protein ANXA8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
36.7 kDa
20 µg/$1,107
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E. coli
His
39.1 kDa
100 µg/$843
ANXA8 / Annexin A8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.7 kDa
20 µg/$150
ANXA8 / Annexin A8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.7 kDa
100 µg/$494
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E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
36.9 kDa
10 µg/$288; 50 µg/$436
ANXA8 / Annexin A8 Protein - 12.5% SDS-PAGE of human ANXA8 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.71 kDa
10 µg/$479; 25 µg/$670
ANXA8 / Annexin A8 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).