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Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
Gene Name: | annexin A4 |
Synonyms: | ANXA4, 35-beta calcimedin, ANX4, Annexin A4, Annexin IV, Annexin-4, Chromobindin-4, Endonexin I, Lipocortin IV, p32.5, PIG28, Proliferation-inducing gene 28, Protein II, ZAP36, p33/41, PAP-II, PP4-X |
Target Sequences: | NM_001153 NP_001144.1 P09525 |
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