ANTXR1 / TEM8

anthrax toxin receptor 1

ANTXR1 / TEM8 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

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Products

Proteins (16)

Type

Over-Expression Lysate (4)

Recombinant (12)

Target

ANTXR1 / TEM8 (16)

Application

SDS-PAGE (1)

Publications

No (16)

Tag

6His, C-terminus (2)

6His, N-terminus (4)

Fc (1)

GST (1)

GST, N-terminus (1)

Human IgG Fc, C-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (11)

Mouse (3)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (6)

Human Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (2)

Yeast (2)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (4)

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Human ANTXR1 / TEM8 Protein (Recombinant 6His, N-terminus) (aa33-321) - LS-G57109

Source:

Yeast

Tag:

6His, N-terminus

Price:

500 µg/$1,052; 100 µg/$446; 20 µg/$336

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Human ANTXR1 / TEM8 Protein (Recombinant 6His, C-terminus) (Glu33-Lys321) - LS-G39300

Source:

HEK 293 Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.56kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human ANTXR1 / TEM8 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Ser321) - LS-G51022

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human ANTXR1 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 530 amino acids and has a predicted molecular mass of 59.4 kDa. The apparent molecular mass of the protein is approximately 69 kDa in SDS-PAGE under reducing conditions.

Price:

50 µg/$441

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Mouse ANTXR1 / TEM8 Protein (Recombinant 6His, N-terminus) (aa31-319) - LS-G57114

Source:

Yeast

Tag:

6His, N-terminus

Price:

1 mg/$1,973; 100 µg/$570; 20 µg/$395

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Mouse ANTXR1 / TEM8 Protein (Recombinant 6His, N-terminus) (aa31-319) - LS-G57023

Source:

Mammalian Cells

Tag:

6His, N-terminus

Price:

100 µg/$1,116; 20 µg/$461; 1 mg/$3,921

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Human ANTXR1 / TEM8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71875

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$1,107

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Human ANTXR1 / TEM8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71876

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

20 µg/$1,107

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Human ANTXR1 / TEM8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90842

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.06 kDa

Price:

20 µg/$150

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Human ANTXR1 / TEM8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90843

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$150

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Human ANTXR1 / TEM8 Protein (Recombinant Fc) (Met1-Ser321) - LS-G97158

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.4 kDa

Price:

50 µg/$721

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Human ANTXR1 / TEM8 Protein (Recombinant GST, N-terminus) (aa201-305) - LS-G63351

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ANTXR1 / TEM8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108035

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

100 µg/$494

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ANTXR1 / TEM8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111927

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.06 kDa

Price:

100 µg/$494

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Human ANTXR1 / TEM8 Protein (Recombinant GST) (Full Length) - LS-G35682

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse ANTXR1 / TEM8 Protein (Recombinant 6His, N-terminus) (aa31-319) - LS-G56090

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ANTXR1 / TEM8 Protein (Recombinant 6His, C-terminus) (Glu33-Lys321) - LS-G139745

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.6 kDa

Price:

10 µg/$288; 50 µg/$436

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