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ANTXR1 / TEM8
anthrax toxin receptor 1
ANTXR1 / TEM8 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
| Gene Name: | anthrax toxin receptor 1 |
| Synonyms: | ANTXR1, Tumor endothelial marker 8, Anthrax toxin receptor 1, TEM8 |
| Target Sequences: | NM_018153 NP_060623.2 Q9H6X2 |
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ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Yeast
6His, N-terminus
500 µg/$1,052; 100 µg/$446; 20 µg/$336
HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.56kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
HEK 293 Cells
Human IgG Fc, C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ANTXR1 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 530 amino acids and has a predicted molecular mass of 59.4 kDa. The apparent molecular mass of the protein is approximately 69 kDa in SDS-PAGE under reducing conditions.
50 µg/$441
ANTXR1 / TEM8 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$896
ANTXR1 / TEM8 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA
Unconjugated
100 µg/$407
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$330
ANTXR1 / TEM8 Mouse anti-Human Monoclonal (aa481-497) (Azide-free) (200C1339(SB20)) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 mg/$386
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
WB
Unconjugated
100 µl/$424
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$460
Yeast
6His, N-terminus
1 mg/$1,973; 100 µg/$570; 20 µg/$395
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (Tyr382) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (aa19-196) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal (aa315-564) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
250 µl/$456
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ANTXR1 / TEM8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
ANTXR1 / TEM8 Goat anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$941
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