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ANT2 / SLC25A5 is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.
Gene Name: | Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 5 |
Family/Subfamily: | Transporter , Mitochondrial carrier |
Synonyms: | SLC25A5, AAC2, 2F1, ANT 2, ADP/ATP carrier protein, ADP/ATP translocase 2, ADP,ATP carrier protein 2, ATP/ADP translocator isoform-2, T3, ANT2, T2 |
Target Sequences: | NM_001152 NP_001143.2 P05141 |
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