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Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns.
Gene Name: | Acidic (leucine-rich) Nuclear Phosphoprotein 32 Family, Member D |
Family/Subfamily: | ANP32 |
Synonyms: | ANP32D, Pp32 related 2, PP32R2, Tumorigenic protein pp32r2 |
Target Sequences: | NM_012404 NP_036536.2 O95626 |
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