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Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Gene Name: | ankyrin repeat domain 13B |
Synonyms: | ANKRD13B, Ankyrin repeat domain 13B |
Target Sequences: | Q86YJ7 Q86YJ7 |
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