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ANKRD13A
ankyrin repeat domain 13A
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
| Gene Name: | ankyrin repeat domain 13A |
| Synonyms: | ANKRD13A, Ankyrin repeat domain 13, ANKRD13, NY-REN-25 antigen, NY-REN-25, Ankyrin repeat domain 13A, Protein KE03 |
| Target Sequences: | NM_033121 NP_149112.1 Q8IZ07 |
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