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ANKRD12 is a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | ankyrin repeat domain 12 |
Synonyms: | ANKRD12, ANCO-2, ANCO2, Ankyrin repeat domain 12, GAC-1 protein, ANCO1, GAC-1, KIAA0874, Nbla00144 |
Target Sequences: | NM_015208 NP_056023.3 Q6UB98 |
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