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Anillin

anillin, actin binding protein

Anillin is an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: anillin, actin binding protein
Synonyms: ANLN, Actin-binding protein anillin, ANILLIN, Anillin, actin binding protein, Scraps, Scra
Target Sequences: NM_018685 NP_061155.2 Q9NQW6

Publications (1)

1
ANLN truncation causes a familial fatal acute respiratory distress syndrome in Dalmatian dogs. Holopainen S, Hytönen MK, Syrjä P, Arumilli M, Järvinen AK, Rajamäki M, Lohi H. PLoS genetics. 2017 February;13:e1006625. (Human) [Full Text Article] [PubMed:28222102] [PMC:PMC5340406] Related Antibodies: LS-C288200.

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Anillin (3)
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Anillin Protein - 12.5% SDS-PAGE of human ANLN stained with Coomassie Blue
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Wheat Germ Extract
GST
70.29 kDa
2 µg/$439
Anillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
124 kDa
20 µg/$215
Anillin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
124 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).