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Angiogenin / ANG

angiogenin, ribonuclease, RNase A family, 5

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Gene Name: angiogenin, ribonuclease, RNase A family, 5
Synonyms: ANG, Angiogenin, HEL168, ALS9, Ribonuclease 5, RNASE5, Epididymis luminal protein 168, RNase 5
Target Sequences: NM_001145 NP_001136.1 P03950

Publications (2)

1
Differential gene expression in normal esophagus and Barrett's esophagus. Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X. Journal of gastroenterology. 2009 44:897-911. (IHC-P; Human) [PubMed:19468668]
2
Prostate cancer-derived angiogenin stimulates the invasion of prostate fibroblasts. Jones ML, Ewing CM, Isaacsa WB, Getzenberg RH. Journal of cellular and molecular medicine. 2012 16:193-201. (WB; Human) [Full Text Article] [PubMed:21352472] Related Antibodies: LS-C34969.

☰ Filters
Products
Proteins (23)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (5)
Recombinant (17)
Angiogenin / ANG (23)
No (23)
6His, N-terminus (6)
6His-SUMO, N-terminus (2)
GST (1)
His (4)
His-GST (1)
His-T7 (2)
Myc-DDK (Flag) (5)
Bovine (2)
Human (10)
Mouse (7)
Pig (1)
Rat (1)
293T Cells (2)
E. coli (13)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Yeast (2)
Purified (5)
Low endotoxin level (3)
Angiogenin / ANG Protein - Recombinant Angiogenin By SDS-PAGE
Select
E. coli
6His, N-terminus
15.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
Angiogenin / ANG Protein - Recombinant Angiogenin By SDS-PAGE
Select
E. coli
6His, N-terminus
15.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$677; 200 µg/$845; 1 mg/$1,938; 500 µg/$1,485; 5 mg/$2,955; 2 mg/$2,124
Angiogenin / ANG Protein
Select
E. coli
6His, N-terminus
14 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Angiogenin / ANG Protein - Recombinant Angiogenin By SDS-PAGE
Select
E. coli
His-GST
45.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$677; 200 µg/$845; 1 mg/$1,938; 500 µg/$1,485; 5 mg/$2,955; 2 mg/$2,124
Angiogenin / ANG Protein - Recombinant Angiogenin By SDS-PAGE
Select
E. coli
His-T7
17.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Select
E. coli
His
15.5 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.27kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
Angiogenin / ANG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.55 kDa
20 µg/$150
Angiogenin / ANG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.55 kDa
20 µg/$150
Angiogenin / ANG Protein - Purified recombinant protein ANG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
14.1 kDa
20 µg/$1,107
Select
E. coli
122 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
13.53 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Angiogenin / ANG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.55 kDa
100 µg/$494
Angiogenin / ANG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.55 kDa
100 µg/$494
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.3 kDa
10 µg/$269; 50 µg/$368
Angiogenin / ANG Protein - Recombinant  Angiogenin By SDS-PAGE
Select
E. coli
His-T7
18.0 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Angiogenin / ANG Protein - 12.5% SDS-PAGE of human ANG stained with Coomassie Blue
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Wheat Germ Extract
GST
39.27 kDa
2 µg/$439
Angiogenin / ANG Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
15 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
Select
HEK 293 Cells
6His, N-terminus
15 kDa
100 µg/$298
Select
HEK 293 Cells
6His, N-terminus
15 kDa
200 µl/$283
Select
E. coli
His
18.7 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
Angiogenin / ANG Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Angiogenin / ANG Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His-SUMO, N-terminus
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Angiogenin / ANG Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His-SUMO, N-terminus
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Viewing 1-23 of 23 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).