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Angiogenin / ANG

angiogenin, ribonuclease, RNase A family, 5

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Gene Name: angiogenin, ribonuclease, RNase A family, 5
Synonyms: ANG, Angiogenin, HEL168, ALS9, Ribonuclease 5, RNASE5, Epididymis luminal protein 168, RNase 5
Target Sequences: NM_001145 NP_001136.1 P03950

Publications (2)

1
Differential gene expression in normal esophagus and Barrett's esophagus. Wang J, Qin R, Ma Y, Wu H, Peters H, Tyska M, Shaheen NJ, Chen X. Journal of gastroenterology. 2009 44:897-911. (IHC-P; Human) [PubMed:19468668]
2
Prostate cancer-derived angiogenin stimulates the invasion of prostate fibroblasts. Jones ML, Ewing CM, Isaacsa WB, Getzenberg RH. Journal of cellular and molecular medicine. 2012 16:193-201. (WB; Human) [Full Text Article] [PubMed:21352472] Related Antibodies: LS-C34969.

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Products
ELISA Kits (50)
Competitive EIA (3)
Custom (2)
Sandwich (38)
Sandwich CLIA (7)
Angiogenin / ANG (50)
Human (16)
Mouse (8)
Rat (6)
Bovine (1)
Chicken (4)
Guinea pig (3)
Monkey (3)
Pig (4)
Porcine (1)
Rabbit (3)
Sheep (1)
12 x 8-Well Microstrips (6)
96-Well Microplate (6)
96-Well Strip Plate (37)
No (50)
Cell Culture Supernatants (7)
Cell Lysates (3)
Cell Supernatant (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (33)
Serum (34)
Tissue Homogenates (10)
Urine (1)
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Microplate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Microplate
Human
1.638 - 160 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Angiogenin / ANG ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
16 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Microplate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$609
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
Angiogenin / ANG ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
Angiogenin / ANG ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$669
Angiogenin / ANG ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Angiogenin / ANG ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).