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ANAPC7 / APC7

anaphase promoting complex subunit 7

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Gene Name: anaphase promoting complex subunit 7
Synonyms: ANAPC7, Cyclosome subunit 7, APC7
Target Sequences: NM_016238 NP_057322.2 Q9UJX3

Publications (1)

1
Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits. Tran K, Mahr JA, Choi J, Teodoro JG, Green MR, Spector DH. Journal of virology. 2008 82:529-37. [PubMed:17942546] [PMC:PMC2224378]

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ANAPC7 / APC7 (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
ANAPC7 / APC7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.2 kDa
20 µg/$215
ANAPC7 / APC7 Protein - Purified recombinant protein ANAPC7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
63 kDa
20 µg/$1,107
ANAPC7 / APC7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.2 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).