ANAPC5 / APC5

anaphase promoting complex subunit 5

ANAPC5 / APC5 is a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ANAPC5 / APC5 (5)

Publications

No (5)

Tag

GST (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ANAPC5 / APC5 Protein (Recombinant GST) (Full Length) - LS-G33771

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

111.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ANAPC5 / APC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82250

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.9 kDa

Price:

20 µg/$150

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ANAPC5 / APC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101407

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.9 kDa

Price:

100 µg/$494

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Human ANAPC5 / APC5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68467

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.9 kDa

Price:

20 µg/$1,107

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Human ANAPC5 / APC5 Protein (Recombinant GST) (Full Length) - LS-G22261

Source:

E. coli

Tag:

GST

Molecular Weight:

53.6 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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