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ANAPC2 / APC2
anaphase promoting complex subunit 2
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
| Gene Name: | anaphase promoting complex subunit 2 |
| Synonyms: | ANAPC2, KIAA1406, Cyclosome subunit 2, RP11-350O14.5 |
| Target Sequences: | NM_013366 NP_037498.1 Q9UJX6 |
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Antibodies
(24)
Type
Primary
(24)
Target
ANAPC2 / APC2
(24)
Reactivity
Human
(24)
Mouse
(6)
Rat
(5)
Monkey
(2)
Application
IHC
(6)
IHC-P
(3)
WB
(22)
Flo
(8)
ELISA
(9)
IF
(12)
Peptide-ELISA
(1)
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rabbit
(5)
mouse
(19)
Isotype
IgG
(4)
IgG1
(8)
IgG1,k
(6)
IgG2a
(4)
Clonality
monoclonal mc
(18)
polyclonal pc
(6)
Clone
OTI1A6
(2)
OTI1B11
(2)
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(2)
OTI1H8
(2)
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(2)
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(2)
Format
AP Conjugated
(1)
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(1)
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(1)
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(6)
FITC Conjugated
(1)
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(1)
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(1)
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(18)
Epitope
aa604-820
(1)
aa712-746
(1)
aa716-823
(1)
Publications
No
(24)
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI1B12) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B12) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI1A6) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A6) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI1H8) Antibody
Mouse, Rat, Human
Flo, IF, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H8) Antibody
Mouse, Rat, Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI2A1) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A1) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI3E1) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3E1) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ANAPC2 / APC2 Rabbit anti-Human Polyclonal (aa712-746) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
400 µl/$393
ANAPC2 / APC2 Mouse anti-Human Monoclonal (OTI1B11) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B11) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
ANAPC2 / APC2 Rabbit anti-Human Polyclonal (aa604-820) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
ANAPC2 / APC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ANAPC2 / APC2 Mouse anti-Human Monoclonal (aa716-823) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
ANAPC2 / APC2 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
ANAPC2 / APC2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
ANAPC2 / APC2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
ANAPC2 / APC2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ANAPC2 / APC2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
ANAPC2 / APC2 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
ANAPC2 / APC2 Rabbit anti-Human Polyclonal (AP) Antibody
Mouse, Rat, Human
WB
AP Conjugated
20 µl/$275; 100 µl/$389
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