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Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Gene Name: | anaphase promoting complex subunit 13 |
Synonyms: | ANAPC13, APC13, Cylosome subunit 13, Cyclosome subunit 13, SWM1, DKFZP566D193 |
Target Sequences: | NM_015391 CAB43251.1 |
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