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ANAPC1 / APC1
anaphase promoting complex subunit 1
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
| Gene Name: | anaphase promoting complex subunit 1 |
| Synonyms: | ANAPC1, APC1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24 |
| Target Sequences: | NM_022662 NP_073153.1 Q9H1A4 |
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Products
Antibodies
(25)
Proteins
(1)
Type
Primary
(25)
Recombinant
(1)
Target
ANAPC1 / APC1
(26)
Reactivity
Human
(25)
Mouse
(19)
Rat
(8)
Bovine
(1)
Dog
(1)
Application
IHC
(17)
IHC-P
(8)
WB
(10)
Flo
(2)
ELISA
(16)
ICC
(2)
IF
(10)
IP
(3)
Peptide-ELISA
(5)
Host
rabbit
(23)
mouse
(2)
Product Group
IHCPlus
(3)
Isotype
IgG
(21)
IgG1
(2)
Clonality
monoclonal mc
(2)
polyclonal pc
(23)
Clone
7G9B3
(1)
7G9C7
(1)
Format
Unconjugated
(25)
Epitope
pSer355
(3)
290-370 aa
(2)
630-710 aa
(2)
pSer688
(2)
Glu684
(1)
Internal
(1)
aa1311-1360
(1)
aa321-370
(1)
aa500-550
(1)
aa654-703
(1)
pSer377
(1)
Publications
No
(26)
Tag
GST, N-terminus
(1)
Species
Human
(1)
Source
Wheat Germ Extract
(1)
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer377) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (630-710 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa500-550) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
ANAPC1 / APC1 Mouse anti-Human Monoclonal (7G9B3) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µl/$459
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa654-703) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Mouse anti-Human Monoclonal (7G9C7) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer688) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (630-710 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer688) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (Glu684) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (290-370 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (290-370 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa321-370) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$567
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
![ANAPC1 / APC1 Antibody - Anti-APC1 pS355 Antibody - Western Blot. Western blot of Affinity Purified anti-APC1 pS355 antibody shows detection of a band ~215 kD corresponding to phosphorylated human APC1 (arrowhead). Lane 1 shows lysate from asynchronous cells. Lane 2 shows lysate from cells treated with thymidine to synchronize cells at the G1/S boundary. Lane 3 shows lysate from cells treated with nocodazole to synchronize cells at the M phase. Phosphorylated APC1 is mostly present only in cell preparations arrested at cell division. Each lane contains approximately 30 ug of HeLa S3 whole cell lysates separated by 12.5% SDS-PAGE followed by transfer to nitrocellulose. After blocking with 5% non-fat dry milk in TTBS, the membrane was probed with the primary antibody diluted to 1:500 for 1 h at room temperature followed by washes and reaction with a 1:5000 dilution of HRP Gt-a-Rabbit IgG [H&L] MX (LS-C60865) for 45 min at room temperature. ECL reagent was used for detection. Other detection systems will yield similar results. Data contributed by Bing Li, UT Southwestern.](https://lsbio-7d62.kxcdn.com/image2/anapc1-apc1-antibody-phospho-ser355-ls-c18983/62894_5054667.jpg)
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (pSer355) Antibody
Mouse, Dog, Bovine, Rat, Human
ELISA, IP, WB
Unconjugated
100 µg/$567
ANAPC1 / APC1 Rabbit anti-Human Polyclonal (aa1311-1360) Antibody
Mouse, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ANAPC1 / APC1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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of 26
product results
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