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AMOTL2

angiomotin like 2

Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.

Gene Name: angiomotin like 2
Synonyms: AMOTL2, Angiomotin-like protein 2, Angiomotin like 2, LCCP, Leman coiled-coil protein, KIAA0989
Target Sequences: NM_016201 NP_057285.3 Q9Y2J4

Publications (2)

1
IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. Deborah Rotoli, Manuel Morales, María-Del-C Maeso, Julio Ávila, Natalia D Pérez-Rodríguez, Ali Mobasheri, Cornelis J F van Noorden, Pablo Martín-Vasallo. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2019 July;67:481-494. [Full Text Article] [PubMed:30794467] [PMC:PMC6598128] Related Antibodies: LS-C178611.
2
Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy. Rotoli D, Morales M, Ávila J, Maeso MDC, García MDP, Mobasheri A, Martín-Vasallo P. International journal of molecular sciences. 2017 18: (IHC; Human) [Full Text Article] [PubMed:28441737] [PMC:PMC5412470] Related Antibodies: LS-C178611.

☰ Filters
Proteins (4)
Antibodies (2)
ELISA Kits (2)
Custom (2)
Over-Expression Lysate (2)
Primary (2)
Recombinant (2)
AMOTL2 (8)
Human (3)
Mouse (1)
IHC (1)
WB (2)
ELISA (2)
rabbit (2)
polyclonal pc (2)
96-Well Strip Plate (2)
Unconjugated (2)
aa6-235 (1)
No (7)
Yes (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
AMOTL2 Antibody
Select
AMOTL2 Rabbit anti-Human Polyclonal (aa6-235) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
AMOTL2 Antibody - Western blot - Anti-AMOTL2 Picoband antibody
Select
AMOTL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
AMOTL2 Protein - 12.5% SDS-PAGE of human AMOTL2 stained with Coomassie Blue
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Wheat Germ Extract
GST
78.2 kDa
10 µg/$479; 25 µg/$670
AMOTL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
85.7 kDa
20 µg/$215
AMOTL2 Protein - Purified recombinant protein AMOTL2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
85.7 kDa
20 µg/$1,107
AMOTL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
85.7 kDa
100 µg/$710
AMOTL2 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
AMOTL2 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
Viewing 1-8 of 8 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).