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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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AMIGO2
adhesion molecule with Ig-like domain 2
AMIGO2/ALIVIN-1 is a member of a small family of type I membrane proteins containing six leucine rich repeats (LRR), one immunoglobulin domain and cysteine rich LLR -NH2 and -COOH domains. In assays a substrate bound form of AMIGO2 promoted prominent neurite extension and inhibited fasciculation of neurites. A homophilic and heterophilic binding mechanism exists between members of the AMIGO family. AMIGOs are thought to be novel cell adhesion molecules expressed on fiber tracts of neuronal tissues that participate in their formation.
| Gene Name: | adhesion molecule with Ig-like domain 2 |
| Synonyms: | AMIGO2, ALI1, Alivin 1, Alivin-1, Alvin 1, AMIGO-2, Amphoterin induced gene 2, Amphoterin-induced protein 2, Transmembrane protein AMIGO2, DEGA |
| Target Sequences: | NM_181847 NP_862830.1 Q86SJ2 |
Publications (2)
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