ALX4

ALX homeobox 4

ALX4 is a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

ALX4 (2)

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No (2)

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Myc-DDK (Flag) (2)

Species

Human (1)

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293T Cells (1)

HEK 293 Cells (1)

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Human ALX4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91558

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.1 kDa

Price:

20 µg/$150

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ALX4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110579

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.1 kDa

Price:

100 µg/$494

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